Prevagen vs Neuriva: quick answer

Quick Answer

Prevagen and Neuriva are not the same. They use different key listed ingredients, belong to different product lines and come from different manufacturers. Prevagen (Quincy Bioscience) lists apoaequorin and vitamin D. Neuriva (Schiff/Reckitt) lists coffee fruit extract and phosphatidylserine.

No universal winner exists between them. No publicly available head-to-head trial establishes one works better than the other. The better option depends on your ingredient preference, format, budget, health context and tolerance for evidence uncertainty. If memory concerns, medications or health conditions are involved, consult a healthcare professional before starting either product.

Prevagen vs Neuriva: side-by-side comparison

The table below covers the key dimensions shoppers typically compare. No price figures are included because live pricing changes by retailer and promotion.

Prevagen vs Neuriva side-by-side comparison across key categories
Category Prevagen Neuriva What it means for shoppers
Key listed ingredients Apoaequorin (10–40 mg by formula) + Vitamin D (50 mcg) Coffee fruit extract + Phosphatidylserine; B vitamins in some formulas Different molecular approaches — compare based on which ingredient profile you prefer
Product formats Regular, Extra Strength, Professional Formula (capsules); Extra Strength Chewables Original, Plus, Ultra, Sleep, Gummies (varies by retailer) Prevagen varies by dose strength; Neuriva varies by formula blend and format type
Positioning Formulated to support brain health Formulated to support brain performance and focus Both make structure/function claims; neither is a drug
FDA status Dietary supplement; not FDA-approved Dietary supplement; not FDA-approved Neither product undergoes pre-market FDA review for safety or effectiveness
Claims / legal context FTC and NY AG challenged memory/cognitive advertising claims (2017); court ordered maker to cease misleading claims (Dec 2024) Class-action litigation alleged “clinically/scientifically proven” claims were misleading; defendants denied the allegations Read marketing language carefully for both; neither has established drug-level efficacy
Maker Quincy Bioscience Schiff Nutrition (Reckitt) Both established brands with national retail presence
Price comparison View current prices → Check major national retailers for current pricing Compare cost per serving (price ÷ servings), not sticker price alone
Where to buy WellBeUp + major national retailers Major national retailers (in-store and online) WellBeUp carries Prevagen with free shipping; check your preferred retailer for Neuriva

What is Prevagen?

Prevagen is an over-the-counter dietary supplement manufactured by Quincy Bioscience. Its key listed ingredient is apoaequorin, a protein originally derived from bioluminescent jellyfish (Aequorea victoria). The version used in Prevagen is lab-manufactured (recombinant) — the product does not contain harvested jellyfish. Prevagen also lists vitamin D (50 mcg / 2,000 IU) in most formulas.

Prevagen
Prevagen
Quincy Bioscience · Madison, WI
  • Regular Strength — 10 mg apoaequorin, capsule, 30 ct
  • Extra Strength — 20 mg apoaequorin, capsule, 60 ct
  • Professional Formula — 40 mg apoaequorin, capsule, 30 ct
  • Extra Strength Chewables — 20 mg apoaequorin, 30 ct
  • All formulas include 50 mcg vitamin D
📖 Learn more
See the full Prevagen ingredients guide for a detailed breakdown of apoaequorin amounts by formula, inactive ingredients and label context.
Compare Prevagen Formulas at WellBeUp →

Prevagen is sold as a dietary supplement under DSHEA regulations. It is not an FDA-approved drug and is not intended to diagnose, treat, cure or prevent any disease. For evidence and efficacy context, see Does Prevagen Really Work?

What is Neuriva?

Neuriva is a brain health supplement line from Schiff Nutrition (owned by Reckitt). Its key listed ingredients are coffee fruit extract (from Coffea arabica) and phosphatidylserine, a phospholipid found naturally in brain tissue. Some Neuriva formulas also include B vitamins (B6 and B12).

Neuriva
Neuriva
Schiff Nutrition (Reckitt)
  • Neuriva Original — coffee fruit extract + phosphatidylserine, capsule
  • Neuriva Plus — adds B6 and B12, capsule
  • Neuriva Ultra — extended formula, capsule
  • Neuriva Gummies — gummy format with same key listed ingredients
  • Neuriva Sleep — additional sleep-support blend in some formulas
  • Exact formulas and counts vary by retailer

Neuriva is also sold as a dietary supplement under DSHEA. It is not an FDA-approved drug. Neuriva has faced class-action litigation in which plaintiffs alleged that claims describing its ingredients as “clinically tested” or “scientifically proven” to support brain function were false or misleading. The defendants denied those allegations. An appeals court vacated a settlement on standing and jurisdiction grounds; the litigation context remains part of Neuriva’s public record.

Prevagen vs Neuriva ingredients

The two products use entirely different key listed ingredients. There is no ingredient overlap between the base formulas. Use “key listed ingredient” rather than “active ingredient” — these are dietary supplements, not drugs, and “active ingredient” is a pharmaceutical classification.

Ingredient comparison between Prevagen and Neuriva by category
Feature Prevagen Neuriva
Key listed ingredient #1 Apoaequorin (10 mg, 20 mg or 40 mg depending on formula) Coffee fruit extract (Coffea arabica)
Key listed ingredient #2 Vitamin D (50 mcg / 2,000 IU, all formulas) Phosphatidylserine (from sunflower lecithin in many SKUs)
Additional nutrients None listed beyond apoaequorin + vitamin D Vitamin B6 and B12 in Plus and some other formulas
Dosing options Three apoaequorin strengths (10 / 20 / 40 mg); once daily Single-strength base formula; differentiated by blend (Original / Plus / Ultra / Sleep); once daily
Available formats Capsule; chewable tablet (Extra Strength 20 mg) Capsule; gummy; sleep formula; ultra formula (varies by retailer)
Ingredient origin Apoaequorin is lab-manufactured (recombinant protein); not harvested from jellyfish Coffee fruit extract is plant-derived; phosphatidylserine typically from sunflower
Inactive ingredients Vary by SKU — check individual product label Vary by SKU — check individual product label
ℹ️ Label note
Inactive ingredients, excipients and allergen status vary by specific SKU and may change without notice. Check the current product label before purchase if you have dietary restrictions or allergies.

For a deeper breakdown of Prevagen’s ingredient profile, including the mechanism question, digestibility and blood-brain barrier plausibility, see the Prevagen ingredients guide.

Does Prevagen work better than Neuriva?

Available public evidence does not establish that either Prevagen or Neuriva works better than the other for memory or cognitive function. No peer-reviewed head-to-head clinical trial comparing these two specific products is publicly available.

Both products are marketed as dietary supplements under DSHEA structure/function claims — meaning they are formulated to support brain health, not to treat or prevent disease. Structure/function claims do not require the level of clinical evidence required for prescription or OTC drug approvals.

Prevagen’s regulatory and legal history

In January 2017, the FTC and the New York Attorney General charged Quincy Bioscience with making deceptive and unsubstantiated advertising claims that Prevagen improved memory and provided cognitive benefits. The FTC alleged the supporting clinical study failed to show a statistically significant benefit for the overall study population. In December 2024, the FTC announced a court ruling requiring Quincy Bioscience to cease misleading claims related to memory loss. Source: FTC December 2024 statement.

Neuriva’s litigation context

Neuriva has faced separate class-action litigation in which plaintiffs alleged that its marketing representations — including descriptions of key listed ingredients as “clinically tested” or “scientifically proven to improve brain function” — were false or misleading. The defendants (Schiff/Reckitt) denied these allegations. An Eleventh Circuit Court of Appeals decision vacated a prior settlement approval on standing and jurisdiction grounds. This litigation is separate from any FTC action.

⚠️ What this means for shoppers
Marketing claims about memory, focus or brain performance from both brands should be read carefully. As dietary supplements, neither product is required to demonstrate efficacy at the standard applied to drugs. Individual results vary and no outcome is guaranteed for either product.

Prevagen vs Neuriva side effects and safety

No blanket safety ranking between Prevagen and Neuriva is appropriate. Side effects and individual risk depend on the person, their medications and existing health conditions — not only on the supplement.

Reported adverse events associated with Prevagen in the literature and public databases have included nausea, headache and dizziness, among others. Neuriva’s reported events may differ given its different ingredient profile. Neither list is exhaustive, and individual responses vary.

🩺 Talk to a healthcare professional before starting either product if you are:
  • Pregnant or nursing
  • Under 18 years of age
  • Taking prescription or OTC medications
  • Managing any chronic health condition
  • Experiencing new, worsening or unexplained memory concerns — these warrant medical evaluation, not supplement self-treatment

For a detailed safety discussion focused on Prevagen, see Prevagen side effects and safety.

Prevagen vs Neuriva cost

We do not publish static price comparisons between Prevagen and Neuriva because prices change frequently by retailer, formula, count and active promotions. Publishing a price comparison that becomes stale would mislead you.

The right comparison metric is cost per serving — current pack price divided by the number of servings — not sticker price alone. A 60-count pack at a higher sticker price may cost less per day than a 30-count pack at a lower sticker price.

Cost-Per-Serving Formula
Current price
Live product page
÷
Serving count
e.g. 30 or 60
=
Daily cost
True comparison metric

For Prevagen pricing, compare current Prevagen prices at WellBeUp. WellBeUp offers free shipping on all orders, which affects total delivered cost. For a full breakdown, see the Prevagen cost guide. For Neuriva pricing, check your preferred national retailer directly.

💡 Comparison tip
When comparing cost across retailers or between the two brands, always compare the same format and serving count and factor in shipping. A free-shipping option at a slightly higher sticker price is often the better value.

Format and convenience

Format matters if you have preferences about how you take supplements daily.

Prevagen offers capsules across all three apoaequorin strengths (Regular 10 mg, Extra Strength 20 mg, Professional Formula 40 mg) and chewable tablets at the 20 mg Extra Strength level. If you want a stepped-dose approach — starting at a lower strength and moving up — Prevagen’s three-tier structure makes that straightforward.

Neuriva provides more format variety, including capsules (Original, Plus, Ultra), gummies, and a sleep-focused formula. If you prefer a gummy format or want a product that includes B vitamins in the same daily dose, certain Neuriva formulas may align better with that preference.

✓ Format summary
Choose Prevagen if you want stepped-dose options (10 / 20 / 40 mg) in capsule or chewable form. Consider Neuriva if you prefer gummy formats, B vitamin inclusion, or specific sleep-support blends.

Prevagen or Neuriva: which should you choose?

Use the framework below as a starting point. Neither product is universally better — the right choice depends on what matters to you.

Consider Prevagen if you…
  • Prefer a formula built around apoaequorin and vitamin D
  • Want dose flexibility — 10, 20 or 40 mg apoaequorin options
  • Prefer a capsule or chewable tablet format
  • Want to shop at WellBeUp with free shipping and easy formula comparison
  • Want to compare product pages side by side in one place
Consider Neuriva if you…
  • Prefer coffee fruit extract and phosphatidylserine over apoaequorin
  • Want a gummy format option
  • Want B vitamins (B6, B12) included in the same daily supplement
  • Prefer a sleep-support variant
  • Are already buying from a retailer that stocks Neuriva
Ask a healthcare professional first if you…
  • Take prescription or OTC medications — supplement interactions are possible
  • Are pregnant, nursing, under 18, or managing a chronic health condition
  • Are experiencing new, worsening or unexplained memory problems — these require medical evaluation
  • Are considering combining both products or adding either to an existing supplement regimen

Neither Prevagen nor Neuriva is intended to diagnose, treat, cure or prevent memory loss, dementia, Alzheimer’s disease or any other disease. Individual results vary for both products, and no outcome is guaranteed.

Compare all Prevagen formulas at WellBeUp

Regular 10 mg · Extra Strength 20 mg · Professional 40 mg · Extra Strength Chewables. Free shipping on every order.

Shop Prevagen Now →

Prevagen vs Neuriva FAQ

No. Prevagen and Neuriva are different dietary supplements with different key listed ingredients, product lines and makers. Prevagen (Quincy Bioscience) lists apoaequorin and vitamin D. Neuriva (Schiff/Reckitt) lists coffee fruit extract and phosphatidylserine. They are not interchangeable and should not be assumed equivalent.
There is no universal better choice. The two supplements use different ingredient approaches, and neither has established superiority in publicly available head-to-head evidence. The better option depends on your ingredient preference, format, budget, health context and evidence expectations. Consult a healthcare professional if you have specific health concerns.
Prevagen lists apoaequorin (10–40 mg depending on formula) and vitamin D (50 mcg) as its key listed ingredients. Neuriva’s key listed ingredients are coffee fruit extract and phosphatidylserine; some Neuriva formulas also include B vitamins such as B6 and B12. There is no ingredient overlap between the two base products.
Available public evidence does not establish that either product works better than the other for memory or cognitive function. Both are marketed as brain health dietary supplements under DSHEA structure/function claims — not as drugs. No peer-reviewed head-to-head trial comparing the two products is publicly available. Individual results vary for both.
No. Prevagen is a dietary supplement, not a drug. The FDA does not pre-approve dietary supplements for safety or effectiveness before they reach the market. Prevagen’s label must include the required DSHEA disclaimer: “These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.”
No. Neuriva is also a dietary supplement, not an FDA-approved drug. Like all dietary supplements, it is not subject to pre-market FDA review for safety or effectiveness. The same DSHEA disclaimer applies.
No blanket safety ranking between the two products is appropriate. Side effects and risks depend on the individual, the medications they take and their existing health conditions — not only on the supplement. Consult a healthcare professional for guidance specific to your situation, especially if you take medications or manage any health condition.
Do not combine brain health supplements without first consulting a healthcare professional, especially if you take medications, have existing health conditions, are pregnant or nursing, or are under 18. There is no established clinical guidance endorsing the combination of Prevagen and Neuriva. Combining supplements can increase the risk of side effects or interactions.
Pricing changes frequently by formula, serving count, retailer and active promotions. We cannot confirm which costs more without live data on the specific SKUs being compared. To make an accurate comparison, look at the same serving count and calculate total delivered cost — including shipping — for both. See the Prevagen cost guide for a detailed pricing framework.
Older adults should give particular attention to medications they already take and any existing health conditions, and should discuss any new supplement with a clinician before starting. Neither Prevagen nor Neuriva is intended to diagnose, treat, cure or prevent memory loss, dementia, Alzheimer’s disease or any other disease. Memory changes in older adults warrant medical evaluation — not supplement self-treatment.
No. Both Prevagen and Neuriva are dietary supplements, not drugs, and are not intended to diagnose, treat, cure or prevent memory loss, dementia, Alzheimer’s disease or any other disease. If you are experiencing memory concerns — especially new or worsening ones — consult a qualified healthcare professional for proper evaluation.
You can compare all Prevagen formulas — Regular Strength, Extra Strength, Professional Formula and Extra Strength Chewables — at WellBeUp’s Prevagen brand hub with free shipping on every order. Prevagen is also available at major national retailers in-store and online.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. Prevagen and Neuriva are dietary supplements, not drugs, and are not intended to diagnose, treat, cure or prevent any disease. Individual results vary. Consult a qualified healthcare professional before starting any supplement, especially if you are pregnant, nursing, have a medical condition or take medications.

Sources

  1. 1
    Prevagen Official FAQ — Apoaequorin and vitamin D amounts by formula. prevagen.com/pages/faq
  2. 2
    Schiff Vitamins / Neuriva — Official product and research page. schiffvitamins.com — Neuriva research
  3. 3
    U.S. Food and Drug Administration — Questions and Answers: Dietary Supplements. fda.gov — Dietary Supplement Q&A
  4. 4
    FTC Press Release, January 2017 — FTC and NY State Charge Marketers of Prevagen with Deceptive Memory/Cognitive Improvement Claims. ftc.gov — 2017 Prevagen charge
  5. 5
    FTC Press Release, December 2024 — Statement on FTC Win in Lawsuit Against Makers of Prevagen. ftc.gov — December 2024 statement
  6. 6
    Justia — Eleventh Circuit Appeal, Neuriva class-action (22-11232, April 2023). law.justia.com — 22-11232
  7. 7
    RB Settlement — Neuriva class-action settlement site; defendants denied allegations. rbsettlement.com
  8. 8
    NCBI Bookshelf / LiverTox — Apoaequorin background and adverse event context. ncbi.nlm.nih.gov — Apoaequorin